THE MICHAEL CUCCIONE PEDIATRIC ONCOLOGY LABORATORY
Finding a Cure for Childhood Cancer
To ensure that childhood
cancer research continues
to progress to greater heights, the Michael Cuccione
Foundation has reached an agreement to fund the
Michael Cuccione Laboratory for Childhood Cancer
Research at the Research Institute at BC Children's
Your donations will be directly forwarded to
fund ongoing childhood cancer research. The Michael
Cuccione Foundation is committed to educating
you on where your donations are going and how
they are helping the fight against childhood cancer.
The letter below has recently been written by Dr.
Sandra Dunn, molecular biologist, who is working
to find new effective treatments for childhood
cancers in the Michael Cuccione Laboratory for
Childhood Oncology Research:
Dr. Sandra Dunn:
"... One of the most crucial things in
successfully treating childhood cancer is developing
therapies that target the cancer cell's survival,
yet allow healthy cells to remain unscathed.
Finding ways to do this allows children with
cancer to be treated using relatively low doses
of chemotherapy, which is so critical in helping
kids handle treatment and recover strong.
My research group and I are looking at several
common drugs that have been shown to stop the
growth of cancer cells. Through our research,
we've found a key process in cancer cell function
- the interaction of two proteins that help
cancer cells survive treatment; if we can block
the interaction of these proteins, we can destroy
the cancer cells without hurting the healthy
cells. This protein is also found in breast
cancer. So what we learn from this will also
benefit breast cancer.
Our research is also trying to develop new
diagnostic tools for early cancer reoccurrence.
At this time, unfortunately, the available tests
that detect a returned cancer are expensive
and invasive. However, my research has found
a serine protease known as urokinase plasminogen
activator (UPA) that clearly shows when cancer
has returned. It is our hope that this discovery
will lead to the development of a new blood
test, which is especially good news for childhood
cancer survivors because, with long lives before
them, early diagnosis of a relapse is essential
for fast, life-saving treatment..."
Click here to learn more about our Researchers and their study profiles »
Upcoming Fundraising Events
Mark your calendar, come and join us at the following fundraising events! We promise, it will be fun!
2014 Canadian Tire Kick For A Cure
Date: July 12, 2014 details
19th Annual Fundraising Gala 2014
Date: September 20, 2014 details
Checkout our news section to learn about the latest developments taking place at our Childhood Cancer Research Program & The Michael Cuccione Pediatric Oncology Laboratory at the Child & Family Research Insitute, BC Children's Hospital.
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